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A cAMP and Ca(2+) coincidence detector in support of Ca(2+)-induced Ca(2+) release in mouse pancreatic β cells
The blood glucose-lowering hormone glucagon-like peptide-1 (GLP-1) stimulates cAMP production, promotes Ca(2+) influx, and mobilizes an intracellular source of Ca(2+) in pancreatic β cells. Here we provide evidence that these actions of GLP-1 are functionally related: they reflect a process of Ca(2+...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Ltd
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583090/ https://www.ncbi.nlm.nih.gov/pubmed/15860526 http://dx.doi.org/10.1113/jphysiol.2005.087510 |