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Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems
Alzheimer's disease (AD) is a progressive neurodegenerative disease and in its familial form is associated with mutations in the amyloid precursor protein (APP) and the presenilins (PSs). Much data regarding the interactions of APP, its proteolytic fragments and PS have been generated, expandin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583130/ https://www.ncbi.nlm.nih.gov/pubmed/22498202 http://dx.doi.org/10.1186/alzrt108 |