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Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems

Alzheimer's disease (AD) is a progressive neurodegenerative disease and in its familial form is associated with mutations in the amyloid precursor protein (APP) and the presenilins (PSs). Much data regarding the interactions of APP, its proteolytic fragments and PS have been generated, expandin...

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Detalles Bibliográficos
Autores principales: Hunter, Sally, Brayne, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583130/
https://www.ncbi.nlm.nih.gov/pubmed/22498202
http://dx.doi.org/10.1186/alzrt108