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Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

BACKGROUND: The predominant model for regulation of gene expression through DNA methylation is an inverse association in which increased methylation results in decreased gene expression levels. However, recent studies suggest that the relationship between genetic variation, DNA methylation and expre...

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Detalles Bibliográficos
Autores principales: van Eijk, Kristel R, de Jong, Simone, Boks, Marco PM, Langeveld, Terry, Colas, Fabrice, Veldink, Jan H, de Kovel, Carolien GF, Janson, Esther, Strengman, Eric, Langfelder, Peter, Kahn, René S, van den Berg, Leonard H, Horvath, Steve, Ophoff, Roel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583143/
https://www.ncbi.nlm.nih.gov/pubmed/23157493
http://dx.doi.org/10.1186/1471-2164-13-636