Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

BACKGROUND: It is well known that somatotrophic/insulin signaling affects lifespan in experimental animals, and one of the signs of aging is progressive gonadal dysfunction. METHODS: To study the effects of insulin-like growth factor-1 (IGF-1) plasma level on ovaries, we analyzed ovaries isolated fr...

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Detalles Bibliográficos
Autores principales: Słuczanowska-Głąbowska, Sylwia, Laszczyńska, Maria, Piotrowska, Katarzyna, Głąbowski, Wojciech, Kopchick, John J, Bartke, Andrzej, Kucia, Magda, Ratajczak, Mariusz Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583234/
https://www.ncbi.nlm.nih.gov/pubmed/22747742
http://dx.doi.org/10.1186/1757-2215-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583234/
https://www.ncbi.nlm.nih.gov/pubmed/22747742
http://dx.doi.org/10.1186/1757-2215-5-18

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