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Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

BACKGROUND: It is well known that somatotrophic/insulin signaling affects lifespan in experimental animals, and one of the signs of aging is progressive gonadal dysfunction. METHODS: To study the effects of insulin-like growth factor-1 (IGF-1) plasma level on ovaries, we analyzed ovaries isolated fr...

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Detalles Bibliográficos
Autores principales:	Słuczanowska-Głąbowska, Sylwia, Laszczyńska, Maria, Piotrowska, Katarzyna, Głąbowski, Wojciech, Kopchick, John J, Bartke, Andrzej, Kucia, Magda, Ratajczak, Mariusz Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583234/ https://www.ncbi.nlm.nih.gov/pubmed/22747742 http://dx.doi.org/10.1186/1757-2215-5-18

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