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Short hairpin RNA targeting Twist1 suppresses cell proliferation and improves chemosensitivity to cisplatin in HeLa human cervical cancer cells

Development of multidrug resistance (MDR) remains a major hurdle to successful cancer chemotherapy and MDR1/P-gp overexpression is believed to be mainly responsible for MDR of tumor cells. Twist1, which is a highly conserved transcription factor that belongs to the family of basic helix-loop-helix p...

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Detalles Bibliográficos
Autores principales: ZHU, KEXIU, CHEN, LIHONG, HAN, XIAOBING, WANG, JIA, WANG, JUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583405/
https://www.ncbi.nlm.nih.gov/pubmed/22245869
http://dx.doi.org/10.3892/or.2012.1633