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Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells

Sulindac, a non-steroidal anti-inflammatory drug, suppresses carcinogenesis and inhibits growth of tumor cells. Pyrrolidine dithiocarbamate (PDTC), a potent NF-κB inhibitor, has been also identified as a potential anti-neoplastic agent. We hypothesized that combination of sulindac and PDTC could res...

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Detalles Bibliográficos
Autores principales: JAKUBOWSKA-MUĆKA, ANNA, SIEŃKO, JACEK, ZAPAŁA, ŁUKASZ, WOLNY, RAFAŁ, LASEK, WITOLD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583429/
https://www.ncbi.nlm.nih.gov/pubmed/22266802
http://dx.doi.org/10.3892/or.2012.1639