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Accurate Identification and Analysis of Human mRNA Isoforms Using Deep Long Read Sequencing

Precise identification of RNA-coding regions and transcriptomes of eukaryotes is a significant problem in biology. Currently, eukaryote transcriptomes are analyzed using deep short-read sequencing experiments of complementary DNAs. The resulting short-reads are then aligned against a genome and anno...

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Detalles Bibliográficos
Autores principales: Tilgner, Hagen, Raha, Debasish, Habegger, Lukas, Mohiuddin, Mohammed, Gerstein, Mark, Snyder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583448/
https://www.ncbi.nlm.nih.gov/pubmed/23450794
http://dx.doi.org/10.1534/g3.112.004812