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Accurate Identification and Analysis of Human mRNA Isoforms Using Deep Long Read Sequencing
Precise identification of RNA-coding regions and transcriptomes of eukaryotes is a significant problem in biology. Currently, eukaryote transcriptomes are analyzed using deep short-read sequencing experiments of complementary DNAs. The resulting short-reads are then aligned against a genome and anno...
Autores principales: | Tilgner, Hagen, Raha, Debasish, Habegger, Lukas, Mohiuddin, Mohammed, Gerstein, Mark, Snyder, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583448/ https://www.ncbi.nlm.nih.gov/pubmed/23450794 http://dx.doi.org/10.1534/g3.112.004812 |
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