On the Mutational Topology of the Bacterial Genome

By sequencing the genomes of 34 mutation accumulation lines of a mismatch-repair defective strain of Escherichia coli that had undergone a total of 12,750 generations, we identified 1625 spontaneous base-pair substitutions spread across the E. coli genome. These mutations are not distributed at rand...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Patricia L., Hanson, Andrew J., Lee, Heewook, Popodi, Ellen M., Tang, Haixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583449/
https://www.ncbi.nlm.nih.gov/pubmed/23450823
http://dx.doi.org/10.1534/g3.112.005355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583449/
https://www.ncbi.nlm.nih.gov/pubmed/23450823
http://dx.doi.org/10.1534/g3.112.005355

Ejemplares similares