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On the Mutational Topology of the Bacterial Genome

By sequencing the genomes of 34 mutation accumulation lines of a mismatch-repair defective strain of Escherichia coli that had undergone a total of 12,750 generations, we identified 1625 spontaneous base-pair substitutions spread across the E. coli genome. These mutations are not distributed at rand...

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Detalles Bibliográficos
Autores principales:	Foster, Patricia L., Hanson, Andrew J., Lee, Heewook, Popodi, Ellen M., Tang, Haixu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2013
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583449/ https://www.ncbi.nlm.nih.gov/pubmed/23450823 http://dx.doi.org/10.1534/g3.112.005355

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