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Molecular and genomic approach for understanding the gene-environment interaction between Nrf2 deficiency and carcinogenic nickel-induced DNA damage
Nickel (II) is a toxic and carcinogenic metal which induces a redox imbalance following oxidative stress. Nuclear factor erythroid-2 related factor 2 (Nrf2) is a redox factor that regulates oxidation/reduction status and consequently mediates cytoprotective responses against exposure to environmenta...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583472/ https://www.ncbi.nlm.nih.gov/pubmed/23023193 http://dx.doi.org/10.3892/or.2012.2057 |