Camptothecin nanocolloids based on N,N,N-trimethyl chitosan: Efficient suppression of growth of multiple myeloma in a murine model

Camptothecin (CPT) exhibits very strong antitumor effects by inhibiting the activity of DNA topoisomerase I, but its application is greatly limited due to its low solubility and the instability of the active lactone form. To overcome these shortcomings, in the present study, we prepared novel campto...

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Detalles Bibliográficos
Autores principales: LI, ZHENGGUANG, LI, XINGYI, CAO, ZHIXING, XU, YOUZHI, LIN, HONGJUN, ZHAO, YINGLAN, WEI, YUQUAN, QIAN, ZHIYONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583474/
https://www.ncbi.nlm.nih.gov/pubmed/22245938
http://dx.doi.org/10.3892/or.2012.1635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583474/
https://www.ncbi.nlm.nih.gov/pubmed/22245938
http://dx.doi.org/10.3892/or.2012.1635

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