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Suppression of FUT1 attenuates cell proliferation in the HER2-overexpressing cancer cell line NCI-N87

Lewis Y (LeY) antigen is an oligosaccharide that is highly expressed at the cell surface in various human cancers. Increased LeY expression activates epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) and promotes cell proliferation in EGFR-overexpressing cel...

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Detalles Bibliográficos
Autores principales: KAWAI, SADAYUKI, KATO, SHUNSUKE, IMAI, HIROO, OKADA, YOSHINARI, ISHIOKA, CHIKASHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583482/
https://www.ncbi.nlm.nih.gov/pubmed/23128605
http://dx.doi.org/10.3892/or.2012.2120