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Silencing of the hTERT gene through RNA interference induces apoptosis via Bax/Bcl-2 in human glioma cells
Glioma cells are characterized by their invasiveness and resistance to conventional therapeutics. The downregulation of human telomerase reverse transcriptase (hTERT) can lead to decreased cell proliferation and/or the induction of apoptotic cell death in cancer cells but has rarely been reported in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583528/ https://www.ncbi.nlm.nih.gov/pubmed/22895663 http://dx.doi.org/10.3892/or.2012.1952 |