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Continuous inhibition of epidermal growth factor receptor phosphorylation by erlotinib enhances antitumor activity of chemotherapy in erlotinib-resistant tumor xenografts
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, has been shown to have benefits for non-small cell lung cancer and pancreatic cancer patients; however, almost all patients develop progressive disease during the therapy. On the other hand, it has been reported that a tumor c...
Autores principales: | IWAI, TOSHIKI, MORIYA, YOICHIRO, SHIRANE, MASATOSHI, FUJIMOTO-OUCHI, KAORI, MORI, KAZUSHIGE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583539/ https://www.ncbi.nlm.nih.gov/pubmed/22209766 http://dx.doi.org/10.3892/or.2011.1614 |
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