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Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer

Altered metabolism is one of the most significant features of cancer cells. ATP citrate lyase (ACL), a key enzyme in de novo lipid synthesis, has been reported to be overexpressed or activated in several cancer types. To determine the role of ACL in ovarian cancer progression, we detected ACL expres...

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Detalles Bibliográficos
Autores principales: WANG, YU, WANG, YUNXIA, SHEN, LIANG, PANG, YINGXIN, QIAO, ZHEN, LIU, PEISHU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583602/
https://www.ncbi.nlm.nih.gov/pubmed/22266777
http://dx.doi.org/10.3892/or.2012.1638