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Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer
Altered metabolism is one of the most significant features of cancer cells. ATP citrate lyase (ACL), a key enzyme in de novo lipid synthesis, has been reported to be overexpressed or activated in several cancer types. To determine the role of ACL in ovarian cancer progression, we detected ACL expres...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583602/ https://www.ncbi.nlm.nih.gov/pubmed/22266777 http://dx.doi.org/10.3892/or.2012.1638 |