MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion

MG132 as a proteasome inhibitor can induce apoptotic cell death in lung cancer cells. However, little is known about the toxicological cellular effects of MG132 on normal primary lung cells. Here, we investigated the effects of N-acetyl cysteine (NAC) and vitamin C (well known antioxidants) or L-but...

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Detalles Bibliográficos
Autores principales: PARK, WOO HYUN, KIM, SUHN HEE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583605/
https://www.ncbi.nlm.nih.gov/pubmed/22266922
http://dx.doi.org/10.3892/or.2012.1642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583605/
https://www.ncbi.nlm.nih.gov/pubmed/22266922
http://dx.doi.org/10.3892/or.2012.1642

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