BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells

Adenosine monophosphate-activated protein kinase (AMPK) is a principal intracellular energy sensor which regulates energy producing pathways and energy requiring pathways when the cellular AMP/ATP ratio is altered. BML-275 (compound C), a well-known inhibitor of AMPK, has been found to induce apopto...

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Detalles Bibliográficos
Autores principales: DUONG, HONG-QUAN, HWANG, JAE SEOK, KIM, HEE JEONG, SEONG, YEON-SUN, BAE, INSOO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583630/
https://www.ncbi.nlm.nih.gov/pubmed/23076030
http://dx.doi.org/10.3892/ijo.2012.1672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583630/
https://www.ncbi.nlm.nih.gov/pubmed/23076030
http://dx.doi.org/10.3892/ijo.2012.1672

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