A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells

In cancer cells integrins modulate important cellular events that regulate the metastasic cascade which involves detachment from the tumor mass, dissemination and attachment to the oncogenic niche. The α5β1, αvβ3 and αvβ5 integrins are widely expressed in different cancer types and recognize the tri...

Descripción completa

Detalles Bibliográficos
Autores principales: RUSSO, MARIKA A., PAOLILLO, MAYRA, SANCHEZ-HERNANDEZ, YULY, CURTI, DANIELA, CIUSANI, EMILIO, SERRA, MASSIMO, COLOMBO, LINO, SCHINELLI, SERGIO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583633/
https://www.ncbi.nlm.nih.gov/pubmed/23174862
http://dx.doi.org/10.3892/ijo.2012.1708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583633/
https://www.ncbi.nlm.nih.gov/pubmed/23174862
http://dx.doi.org/10.3892/ijo.2012.1708

Ejemplares similares