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N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells

Doxorubicin has been used clinically to treat various types of cancer, and yet the molecular mode of actions of doxorubicin remains to be fully unraveled. In this study, we investigated the effect of doxorubicin on cultured ovarian cancer cells (CaOV3). MTT assay data showed that doxorubicin inhibit...

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Detalles Bibliográficos
Autores principales: BRUM, GABRIELLA, CARBONE, THOMAS, STILL, ERIC, CORREIA, VENDITA, SZULAK, KEVIN, CALIANESE, DAVID, BEST, CHARLES, CAMMARATA, GARRET, HIGGINS, KATELYN, JI, FANG, DI, WEN, WAN, YINSHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583638/
https://www.ncbi.nlm.nih.gov/pubmed/23128467
http://dx.doi.org/10.3892/ijo.2012.1680