Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice

Degradation of the extracellular matrix (ECM) plays a critical role in the formation of tumors and metastasis and has been found to correlate with the aggressiveness of tumor growth and invasiveness of cancer. Ascorbic acid, which is known to be essential for the structural integrity of the intercel...

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Detalles Bibliográficos
Autores principales: CHA, JOHN, ROOMI, M. WAHEED, IVANOV, VADIM, KALINOVSKY, TATIANA, NIEDZWIECKI, ALEKSANDRA, RATH, MATTHIAS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583641/
https://www.ncbi.nlm.nih.gov/pubmed/23175106
http://dx.doi.org/10.3892/ijo.2012.1712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583641/
https://www.ncbi.nlm.nih.gov/pubmed/23175106
http://dx.doi.org/10.3892/ijo.2012.1712

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