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Function and cancer genomics of FAT family genes
FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT1 and FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ-secretase to release intracellular domain (ICD)....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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D.A. Spandidos
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583642/ https://www.ncbi.nlm.nih.gov/pubmed/23076869 http://dx.doi.org/10.3892/ijo.2012.1669 |