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Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer

Neutral endopeptidase (NEP) is a cell-surface peptidase that inhibits prostate cancer cell growth partly via inhibition of Akt kinase. We investigated the antitumor effects of an adenovirus gene delivery system (AdNEP) to restore NEP expression in DU145 prostate cancer cells in combination with pacl...

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Detalles Bibliográficos
Autores principales: IIDA, KATSUYUKI, ZHENG, RONG, SHEN, RUOQIAN, NANUS, DAVID M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583657/
https://www.ncbi.nlm.nih.gov/pubmed/22895534
http://dx.doi.org/10.3892/ijo.2012.1586