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Is intracellular pH a clock for mitosis?

Experiments have shown that the intracellular pH of many cells rises to a maximum at the onset of mitosis, subsequently decreasing 0.3 to 0.5 pH units by the end of mitosis. This result, and observations that tubulin net charge depends strongly on pH, may be critical for microtubule (MT) dynamics du...

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Detalles Bibliográficos
Autores principales: Gagliardi, L John, Shain, Daniel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583677/
https://www.ncbi.nlm.nih.gov/pubmed/23402214
http://dx.doi.org/10.1186/1742-4682-10-8