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PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus
BACKGROUND: The inactivation of c-Jun N-terminal kinase (JNK) is associated with anti-apoptotic and anti-inflammatory effects in cerebral ischemia, which can be induced by an imbalance between upstream phosphatases and kinases. RESULT: Mitogen-activated protein kinase phosphatase 7 (MKP-7) was upreg...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583678/ https://www.ncbi.nlm.nih.gov/pubmed/23280045 http://dx.doi.org/10.1186/1471-2202-14-1 |