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PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus

BACKGROUND: The inactivation of c-Jun N-terminal kinase (JNK) is associated with anti-apoptotic and anti-inflammatory effects in cerebral ischemia, which can be induced by an imbalance between upstream phosphatases and kinases. RESULT: Mitogen-activated protein kinase phosphatase 7 (MKP-7) was upreg...

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Detalles Bibliográficos
Autores principales:	Zhu, JianXi, Shen, Wei, Gao, Li, Gu, Hao, Shen, ShuTong, Wang, Yi, Wu, HuiWen, Guo, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583678/ https://www.ncbi.nlm.nih.gov/pubmed/23280045 http://dx.doi.org/10.1186/1471-2202-14-1

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