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Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

Glioblastoma multiforme is the most common primary brain tumor and one of the most aggressive types of cancer in adults. Survival signaling and apoptosis resistance are hallmarks of malignant glioma cells. However, recent studies have shown that other types of cell death such as autophagy can be ind...

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Detalles Bibliográficos
Autores principales: OLSEN, BIRGITTE B., SVENSTRUP, TINA H., GUERRA, BARBARA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583692/
https://www.ncbi.nlm.nih.gov/pubmed/23007634
http://dx.doi.org/10.3892/ijo.2012.1635