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Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells

Emergence of androgen-independent cancer cells during androgen deprivation therapy presents a significant challenge to successful treatment outcomes in prostate cancer. Elucidating the role of androgen deprivation in the transition from an androgen-dependent to an androgen-independent state may enab...

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Detalles Bibliográficos
Autores principales: LIU, TIANCHENG, WU, LISA Y., FULTON, MELODY D., JOHNSON, JACQUELINE M., BERKMAN, CLIFFORD E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583693/
https://www.ncbi.nlm.nih.gov/pubmed/23041906
http://dx.doi.org/10.3892/ijo.2012.1649