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Lung CD8+ T cells in COPD have increased expression of bacterial TLRs

BACKGROUND: Toll-like receptors (TLRs) on T cells can modulate their responses, however, the extent and significance of TLR expression by lung T cells, NK cells, or NKT cells in chronic obstructive pulmonary disease (COPD) is unknown. METHODS: Lung tissue collected from clinically-indicated resectio...

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Detalles Bibliográficos
Autores principales: Freeman, Christine M, Martinez, Fernando J, Han, MeiLan K, Washko,, George R, McCubbrey, Alexandra L, Chensue, Stephen W, Arenberg, Douglas A, Meldrum, Catherine A, McCloskey, Lisa, Curtis, Jeffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583694/
https://www.ncbi.nlm.nih.gov/pubmed/23374856
http://dx.doi.org/10.1186/1465-9921-14-13