Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1 in the gastric epithelium

BACKGROUND: Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. We report an investigation into the effect of HRH2 promoter polymorphism (rs2607474 G...

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Detalles Bibliográficos
Autores principales: Nomura, Tomoe, Tahara, Tomomitsu, Shiroeda, Hisakazu, Minato, Takahiro, Matsue, Yasuhiro, Hayashi, Ranji, Matsunaga, Kazuhiro, Otsuka, Toshimi, Nakamura, Masakatsu, Toshikuni, Nobuyuki, Shibata, Tomoyuki, Arisawa, Tomiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583698/
https://www.ncbi.nlm.nih.gov/pubmed/23280118
http://dx.doi.org/10.1186/1471-230X-13-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583698/
https://www.ncbi.nlm.nih.gov/pubmed/23280118
http://dx.doi.org/10.1186/1471-230X-13-1

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