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OCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma

BACKGROUND: OCT4 and BIRC5 are preferentially expressed in human cancer cells and mediate cancer cell survival and tumor maintenance. However, the molecular mechanism that regulates OCT4 and BIRC5 expression is not well characterized. METHODS: By manipulating OCT4 and BIRC5 expression in hepatocellu...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Li, Chunguang, Shen, Shuwen, Yan, Yan, Ji, Weidan, Wang, Jinghan, Qian, Haihua, Jiang, Xiaoqing, Li, Zhigang, Wu, Mengchao, Zhang, Ying, Su, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583731/
https://www.ncbi.nlm.nih.gov/pubmed/23433354
http://dx.doi.org/10.1186/1471-2407-13-82