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Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases

Malignant mesothelioma (MM) is an aggressive and highly chemoresistant tumour. Although cisplatin is used in frontline therapy of this disease treatment remains palliative at best. The biochemical pathways activated by cisplatin and the mechanisms of resistance in mesothelioma cells are poorly under...

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Detalles Bibliográficos
Autores principales: CREGAN, INEZ L., DHARMARAJAN, ARUN M., FOX, SIMON A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583754/
https://www.ncbi.nlm.nih.gov/pubmed/23229133
http://dx.doi.org/10.3892/ijo.2012.1715