Molecular Interactions of Prodiginines with the BH3 Domain of Anti-Apoptotic Bcl-2 Family Members

Prodigiosin and obatoclax, members of the prodiginines family, are small molecules with anti-cancer properties that are currently under preclinical and clinical trials. The molecular target(s) of these agents, however, is an open question. Combining experimental and computational techniques we find...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosseini, Ali, Espona-Fiedler, Margarita, Soto-Cerrato, Vanessa, Quesada, Roberto, Pérez-Tomás, Ricardo, Guallar, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583838/
https://www.ncbi.nlm.nih.gov/pubmed/23460874
http://dx.doi.org/10.1371/journal.pone.0057562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583838/
https://www.ncbi.nlm.nih.gov/pubmed/23460874
http://dx.doi.org/10.1371/journal.pone.0057562

Ejemplares similares