Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort

OBJECTIVE: The pathogenic mechanism of anti-tuberculosis (anti-TB) drug-induced hepatitis is associated with drug metabolizing enzymes. No tagging single-nucleotide polymorphisms (tSNPs) of cytochrome P450 2E1(CYP2E1) in the risk of anti-TB drug-induced hepatitis have been reported. The present stud...

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Detalles Bibliográficos
Autores principales: Tang, Shaowen, Lv, Xiaozhen, Zhang, Yuan, Wu, Shanshan, Yang, Zhirong, Xia, Yinyin, Tu, Dehua, Deng, Peiyuan, Ma, Yu, Chen, Dafang, Zhan, Siyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583841/
https://www.ncbi.nlm.nih.gov/pubmed/23460870
http://dx.doi.org/10.1371/journal.pone.0057526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583841/
https://www.ncbi.nlm.nih.gov/pubmed/23460870
http://dx.doi.org/10.1371/journal.pone.0057526

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