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Cytochrome P450 2E1 Gene Polymorphisms/Haplotypes and Anti-Tuberculosis Drug-Induced Hepatitis in a Chinese Cohort
OBJECTIVE: The pathogenic mechanism of anti-tuberculosis (anti-TB) drug-induced hepatitis is associated with drug metabolizing enzymes. No tagging single-nucleotide polymorphisms (tSNPs) of cytochrome P450 2E1(CYP2E1) in the risk of anti-TB drug-induced hepatitis have been reported. The present stud...
Autores principales: | Tang, Shaowen, Lv, Xiaozhen, Zhang, Yuan, Wu, Shanshan, Yang, Zhirong, Xia, Yinyin, Tu, Dehua, Deng, Peiyuan, Ma, Yu, Chen, Dafang, Zhan, Siyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583841/ https://www.ncbi.nlm.nih.gov/pubmed/23460870 http://dx.doi.org/10.1371/journal.pone.0057526 |
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