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Established breast cancer stem cell markers do not correlate with in vivo tumorigenicity of tumor-initiating cells
The tumor-initiating capacity of primary human breast cancer cells is maintained in vitro by culturing these cells as spheres/aggregates. Inoculation of small cell numbers derived from these non-adherent cultures leads to rapid xenograft tumor formation in mice. Accordingly, injection of more differ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583871/ https://www.ncbi.nlm.nih.gov/pubmed/23042145 http://dx.doi.org/10.3892/ijo.2012.1654 |