Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity

The fetal transcription factor PLAG1 is found to be overexpressed in cancers, and has been suggested to bind the insulin like growth factor 2 (IGF2) P3 promoter, and to activate the IGF2 gene. The expression of IGF2 has partly been linked to loss of CTCF-dependent chromatin insulator function at the...

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Detalles Bibliográficos
Autores principales: AKHTAR, MONIRA, HOLMGREN, CLAES, GÖNDÖR, ANITA, VESTERLUND, MATTIAS, KANDURI, CHANDRASEKHAR, LARSSON, CATHARINA, EKSTRÖM, TOMAS J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583874/
https://www.ncbi.nlm.nih.gov/pubmed/23023303
http://dx.doi.org/10.3892/ijo.2012.1641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583874/
https://www.ncbi.nlm.nih.gov/pubmed/23023303
http://dx.doi.org/10.3892/ijo.2012.1641

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