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Targeting PI3Kδ: One man’s meat is another man’s poison
We have recently uncovered the indispensable role of phosphoinositide-3-kinase δ (PI3Kδ) at different stages of the canonical killing pathway of cytotoxic T lymphocytes (CTLs). The interception of PI3Kδ−conveyed signals has been considered a valuable therapeutic strategy in oncology. However, our ob...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583912/ https://www.ncbi.nlm.nih.gov/pubmed/23482629 http://dx.doi.org/10.4161/onci.22272 |