Hypoxia-driven immunosuppression contributes to the pre-metastatic niche

Primary tumor cells create favorable microenvironments in secondary organs, termed pre-metastatic niches, that promote the formation of metastases. Using immune competent syngenic breast cancer mouse models, we have recently demonstrated that factors secreted by hypoxic tumor cells condition pre-met...

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Detalles Bibliográficos
Autores principales: Sceneay, Jaclyn, Parker, Belinda S., Smyth, Mark J., Möller, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583916/
https://www.ncbi.nlm.nih.gov/pubmed/23482904
http://dx.doi.org/10.4161/onci.22355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583916/
https://www.ncbi.nlm.nih.gov/pubmed/23482904
http://dx.doi.org/10.4161/onci.22355

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