An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells

One of the driving forces of oncogenesis is tetraploidy, a duplication of the DNA content that, upon asymmetric cell division or progressive chromosome loss, can originate aneuploidy. Recent findings from our group indicate the existence of an immunosurveillance system that eliminates tetraploid can...

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Detalles Bibliográficos
Autores principales: Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Kepp, Oliver, Galluzzi, Lorenzo, Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583917/
https://www.ncbi.nlm.nih.gov/pubmed/23482968
http://dx.doi.org/10.4161/onci.22409