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The adenosinergic system in cancer: Key therapeutic target

High amounts of adenosine are released in the tumor mass. Depending on the levels of adenosine, as well as on the receptor subtypes that are expressed by immune cells, adenosine can affect tumor growth in different fashions. Specifically targeting CD73, the rate-limiting enzyme for the extracellular...

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Detalles Bibliográficos
Autores principales: Sorrentino, Rosalinda, Pinto, Aldo, Morello, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583919/
https://www.ncbi.nlm.nih.gov/pubmed/23483072
http://dx.doi.org/10.4161/onci.22448