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In situ conversion of tumors into autologous tumor-associated antigen vaccines by intratumoral injection of α-gal glycolipids
The immunogenicity of autologous tumor-associated antigens (TAAs) is markedly increased upon the intratumoral injection of α-gal glycolipids, which insert into tumor cell membranes. The binding of natural anti-Gal antibodies to these glycolipids activates the complement system and recruits antigen-p...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583920/ https://www.ncbi.nlm.nih.gov/pubmed/23483105 http://dx.doi.org/10.4161/onci.22449 |