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Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy

Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies.

Detalles Bibliográficos
Autores principales: Zhou, Qi, Buchholz, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583925/
https://www.ncbi.nlm.nih.gov/pubmed/23483777
http://dx.doi.org/10.4161/onci.22566