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Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy
Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583925/ https://www.ncbi.nlm.nih.gov/pubmed/23483777 http://dx.doi.org/10.4161/onci.22566 |