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Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy
Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583925/ https://www.ncbi.nlm.nih.gov/pubmed/23483777 http://dx.doi.org/10.4161/onci.22566 |
| _version_ | 1782475507687751680 |
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| author | Zhou, Qi Buchholz, Christian J. |
| author_facet | Zhou, Qi Buchholz, Christian J. |
| author_sort | Zhou, Qi |
| collection | PubMed |
| description | Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies. |
| format | Online Article Text |
| id | pubmed-3583925 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-35839252013-03-11 Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy Zhou, Qi Buchholz, Christian J. Oncoimmunology Author's View Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies. Landes Bioscience 2013-01-01 /pmc/articles/PMC3583925/ /pubmed/23483777 http://dx.doi.org/10.4161/onci.22566 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Zhou, Qi Buchholz, Christian J. Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title | Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title_full | Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title_fullStr | Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title_full_unstemmed | Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title_short | Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy |
| title_sort | cell type specific gene delivery by lentiviral vectors: new options in immunotherapy |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583925/ https://www.ncbi.nlm.nih.gov/pubmed/23483777 http://dx.doi.org/10.4161/onci.22566 |
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