Human MHC Class I-restricted high avidity CD4(+) T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo

In this study, we generated human MHC Class I-restricted CD4(+) T cells specific for Epstein-Barr virus (EBV) and cytomegalovirus (CMV), two herpesviridae associated with lymphoma, nasopharyngeal carcinoma and medulloblastoma, respectively. Retroviral transfer of virus-specific, HLA-A2-restricted TC...

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Detalles Bibliográficos
Autores principales: Xue, Shao-An, Gao, Liquan, Ahmadi, Maryam, Ghorashian, Sara, Barros, Rafael D, Pospori, Constandina, Holler, Angelika, Wright, Graham, Thomas, Sharyn, Topp, Max, Morris, Emma C, Stauss, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583927/
https://www.ncbi.nlm.nih.gov/pubmed/23483821
http://dx.doi.org/10.4161/onci.22590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583927/
https://www.ncbi.nlm.nih.gov/pubmed/23483821
http://dx.doi.org/10.4161/onci.22590

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