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Involvement of STAT3 in immune evasion during lung tumorigenesis

In a recent study, we have shown that STAT3 expressed by tumor cells blunts antitumor immunity during carcinogen-induced lung tumorigenesis. STAT3 inhibits the production of pro-inflammatory chemokines and MHC Class I chain-related gene A. In contrast, STAT3 promotes the expression of MHC class I mo...

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Detalles Bibliográficos
Autores principales: Kida, Hiroshi, Ihara, Shoichi, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583932/
https://www.ncbi.nlm.nih.gov/pubmed/23482587
http://dx.doi.org/10.4161/onci.22653