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Biogenesis of RNA Polymerases II and III Requires the Conserved GPN Small GTPases in Saccharomyces cerevisiae

The GPN proteins are a poorly characterized and deeply evolutionarily conserved family of three paralogous small GTPases, Gpn1, 2, and 3. The founding member, GPN1/NPA3/XAB1, is proposed to function in nuclear import of RNA polymerase II along with a recently described protein called Iwr1. Here we s...

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Detalles Bibliográficos
Autores principales: Minaker, Sean W., Filiatrault, Megan C., Ben-Aroya, Shay, Hieter, Philip, Stirling, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584002/
https://www.ncbi.nlm.nih.gov/pubmed/23267056
http://dx.doi.org/10.1534/genetics.112.148726