PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs

Preferentially expressed antigen in melanoma (PRAME) has been described as a cancer-testis antigen and is associated with leukaemias and solid tumours. Here we show that PRAME gene transcription in leukaemic cell lines is rapidly induced by exposure of cells to bacterial PAMPs (pathogen associated m...

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Detalles Bibliográficos
Autores principales: Wadelin, Frances R., Fulton, Joel, Collins, Hilary M., Tertipis, Nikolaos, Bottley, Andrew, Spriggs, Keith A., Falcone, Franco H., Heery, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584020/
https://www.ncbi.nlm.nih.gov/pubmed/23460923
http://dx.doi.org/10.1371/journal.pone.0058052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584020/
https://www.ncbi.nlm.nih.gov/pubmed/23460923
http://dx.doi.org/10.1371/journal.pone.0058052

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