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Corneal Endothelial Cells Provide Evidence of Accelerated Cellular Senescence Associated with HIV Infection: A Case-Control Study

BACKGROUND: Cellular senescence may be a key factor in HIV-related premature biological aging. We assessed features of the corneal endothelium that are known to be associated with biological aging, and cellular senescence markers in HIV-infected adults. METHODS: Case-control study of 242 HIV-infecte...

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Detalles Bibliográficos
Autores principales: Pathai, Sophia, Lawn, Stephen D., Shiels, Paul G., Weiss, Helen A., Cook, Colin, Wood, Robin, Gilbert, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584030/
https://www.ncbi.nlm.nih.gov/pubmed/23460854
http://dx.doi.org/10.1371/journal.pone.0057422